Any sample, any environment
Designed to measure the micro-mechanical properties of the most complex materials in challenging environments, the Piuma and Chiaro instruments deliver uncompromised performance for a broad range of applications. Whether you are looking to analyze cell mechanics, hydrogel stiffness, Young’s Modulus of tissues, or define material performance parameters such as adhesion, swelling or degradation, the Piuma and Chiaro instruments deliver you the data you are looking for.
How it works
Our Piuma and Chiaro instruments provide highly accurate and precise measurements of any sample in any environment with high speed and ease of use. These unique capabilities are enabled by making use of the Optics11 patented micro-machined fiber-optical sensors. The Piuma and Chiaro instruments use this sensor to gently push a spherical glass tip on the surface of the sample. By closely monitoring the resulting sample deformation, the instrument can rapidly provide all mechanical details of the indented spot, both under static and dynamic operation.
Our data is good , but the machine is excellent!
We now are able to perform measurements on very low stiffness tissues, with a precision that allows us to study embryos. Colleagues are impressed and come with other challenges that the Piuma easily meets.
The Piuma is a very powerful, reliable, and user-friendly instrument to assess the mechanical properties of living tissue (eg. tissue explants) and engineered tissue in-vitro. Also I found Piuma a very powerful instrument to follow the mechanical properties of growing in-vitro tissues, and study tissue culture evolution over-time.
The Piuma not only allows us to test the same hydrogel samples before and after testing their functionality, but also provides us the ability to probe spatial characteristics. This opens up new capabilities for further understanding of our system's mechanisms, thus aiding in our design process.
Many research groups use our instruments today. Find a brief overview of some recent publications below: