Recent publications

 

 

Mattei, G., Gruca, G., Rijnveld, N., & Ahluwalia, A. (2015). The nano-epsilon dot method for strain rate viscoelastic characterisation of soft biomaterials by spherical nano-indentation. Journal of the mechanical behavior of biomedical materials50, 150-159.

The result of this research is a new version of the epsilon dot method, translated from bulk material testing to nano-indentation measurements. This makes the method applicable for the characterization of (bio)material viscoelastic properties on a typical cell length scale. Nano-epsilon dot can be used complementary to other approaches for viscoelastic characterisation, such as step-response tests (creep, stress-relaxation) or dynamic mechanical analysis (DMA), but has the advantage that the measurements are very quick and starts out of contact, thus avoiding sample pre-stress and degradation.

 

Brancato, V., Ventre, M., Imparato, G., Urciuolo, F., Meo, C., & Netti, P. A. (2016). A straightforward method to produce decellularized dermisbased matrices for tumor cell cultures. Journal of Tissue Engineering and Regenerative Medicine.

In  this  work,  the development and in vitro characterization of a cost-effective, easy-to-produce decellularized dermal matrix is reported.  It proved to be a valid scaffold to study  tumor  cell adhesion, migration and  organization  in  vitro.

 

Yu, X., Hu, Y., Kahn, J. S., Cecconello, A., & Willner, I. (2016). Orthogonal Dual‐Triggered Shape‐Memory DNA‐Based Hydrogels. Chemistry-A European Journal22(41), 14504-14507.

 

Moshtagh, P. R., Pouran, B., Korthagen, N. M., Zadpoor, A. A., & Weinans, H. (2016). Guidelines for an optimized indentation protocol for measurement of cartilage stiffness: The effects of spatial variation and indentation parameters. Journal of Biomechanics.

 

Sarker, B., Singh, R., Zehnder, T., Forgber, T., Alexiou, C., Cicha, I., … & Boccaccini, A. R. (2016). Macromolecular interactions in alginate–gelatin hydrogels regulate the behavior of human fibroblasts. Journal of Bioactive and Compatible Polymers: Biomedical Applications, 0883911516668667. 

 

Swieringa, F., Baaten, C. C., Verdoold, R., Mastenbroek, T. G., Rijnveld, N., van der Laan, K. O., … & Cosemans, J. M. (2016). Platelet Control of Fibrin Distribution and Microelasticity in Thrombus Formation Under Flow. Arteriosclerosis, thrombosis, and vascular biology36(4), 692-699.